Prophylactic bilateral mastectomy

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Psychosocial Implications of Prophylactic Bilateral Mastectomy

Introduction: The removal of healthy breast tissue to prevent the development of breast cancer is seen by many to be a radical surgical intervention. As the numbers of women contemplating such surgery are increasing it is essential that the psychological costs and benefits of prophylactic bilateral mastectomy are established. Aims: This prospective study aims to measure psychological morbidity,...

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Current status of prophylactic mastectomy.

The management of women at high risk for breast cancer presents a clinical dilemma to the health-care provider as well as to the woman herself. Current options include surveillance, prophylactic surgery (mastectomy and/or oophorectomy), and/or chemoprevention. Prophylactic mastectomy, including bilateral prophylactic mastectomy in high-risk women or contralateral prophylactic mastectomy in wome...

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Contralateral prophylactic mastectomy: current perspectives

There has been an increasing trend in the use of contralateral prophylactic mastectomy (CPM) in the United States among women diagnosed with unilateral breast cancer, particularly young women. Approximately one-third of women <40 years old are undergoing CPM in the US. Most studies have shown that the CPM trend is mainly patient-driven, which reflects a changing environment for newly diagnosed ...

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Long-term satisfaction and psychological and social function following bilateral prophylactic mastectomy.

CONTEXT Prophylactic mastectomy is a preventive option for women who wish to reduce their risk of breast cancer. There has been concern about possible negative psychological sequelae following this procedure. However, few data are available regarding long-term satisfaction and psychological and social function following this procedure. OBJECTIVE To evaluate patients' long-term satisfaction an...

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The Role of Bilateral Prophylactic Mastectomy (BPMX) in Women at High Risk of Breast Cancer

Women at high personal risk of breast cancer can be identified from family history using Claus data or from genetic testing for BRCAI and BRCA2 mutations. Women at such risk may be offered surveillance, entry into a chemoprevention trial such as IBIS, or bilateral prophylactic mastectomy (BPMX). Recent published data on the use of Tamoxifen as a chemopreventative agent found reduction of risk i...

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ژورنال

عنوان ژورنال: Cancer

سال: 2002

ISSN: 0008-543X,1097-0142

DOI: 10.1002/cncr.10680